STON2 Rabbit pAb
-YT7374
主要信息
Target
STON2
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, IF, Flow Cyt, ELISA, IHC
MW
100kD (Calculated)
Conjugate/Modification
Unmodified
货号: YT7374
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
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详细信息
推荐稀释比
WB 1:500-2000; IF/ICC1:50-200; ELISA 1:2000-20000; IHC 1:50-200
Note:For IHC,wesuggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004)
Note:For IHC,wesuggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004)
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
This antibody detects endogenous levels of STON2 at Human/Mouse
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
理论分子量
100kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
Synthesized peptide derived from human STON2 AA range: 47-97
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特异性:
This antibody detects endogenous levels of STON2 at Human/Mouse
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基因名称:
STON2 STN2 STNB
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蛋白名称:
STON2
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背景:
This gene encodes a protein which is a membrane protein involved in regulating endocytotic complexes. The protein product is described as one of the clathrin-associated sorting proteins, adaptor molecules which ensure specific proteins are internalized. The encoded protein has also been shown to participate in synaptic vesicle recycling through interaction with synaptotagmin 1 required for neurotransmission. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012],
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功能:
Domain:The Asn-Pro-Phe (NPF) motifs, which are found in proteins involved in the endocytic pathway, mediate the interaction with the EH domain of SYT1, SYT2, EPS15, EPS15R and ITSN1.,Function:Adapter protein involved in endocytic machinery. May be involved in the vesicle recycling. May facilitate clathrin-coated vesicle uncoating.,similarity:Belongs to the Stoned B family.,similarity:Contains 1 MHD (mu homology) domain.,similarity:Contains 1 SHD (stonin homology) domain.,subcellular location:Some fraction is membrane-associated.,subunit:Interacts with the second C2 domain of synaptotagmins SYT1 and SYT2. Interacts with EPS15, EPS15R and ITSN1. Interacts indirectly with the AP-2 adapter complex.,tissue specificity:Ubiquitous.,
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细胞定位:
Cytoplasm . Membrane . Cell junction, synapse, synaptosome . Some fraction is membrane-associated.
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组织表达:
Ubiquitous.
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货号: YT7374
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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