Purified recombinant fragment of CD80 expressed in E. Coli.

CD80 Monoclonal Antibody detects endogenous levels of CD80 protein.

CD80

T-lymphocyte activation antigen CD80

CD80 ;
CD28LG ;
CD28LG1 ;
LAB7 ;
T-lymphocyte activation antigen CD80 ;
Activation B7-1 antigen ;
BB1 ;
CTLA-4 counter-receptor B7.1 ;
B7 ;
CD antigen CD80

The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy. [provided by RefSeq, Aug 2011],

Function:Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Interacts with adenovirus subgroup B fiber proteins and acts as a receptor for these viruses.,tissue specificity:Expressed on activated B-cells, macrophages and dendritic cells.,

Membrane; Single-pass type I membrane protein.

Expressed on activated B-cells, macrophages and dendritic cells.

>>Cell adhesion molecules ;
>>Toll-like receptor signaling pathway ;
>>Intestinal immune network for IgA production ;
>>Type I diabetes mellitus ;
>>Autoimmune thyroid disease ;
>>Systemic lupus erythematosus ;
>>Rheumatoid arthritis ;
>>Allograft rejection ;
>>Graft-versus-host disease ;
>>Viral myocarditis