RRP44 Rabbit pAb
-YN3292
主要信息
Target
RRP44
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB
MW
105kD (Observed)
Conjugate/Modification
Unmodified
货号: YN3292
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
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详细信息
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
This antibody detects endogenous levels of RRP44 at Human/Mouse
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
105kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
Synthesized peptide derived from human RRP44 AA range: 262-312
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特异性:
This antibody detects endogenous levels of RRP44 at Human/Mouse
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基因名称:
DIS3 KIAA1008 RRP44
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蛋白名称:
RRP44
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别名:
Exosome complex exonuclease RRP44 ;
EC 3.1.26.- ;
Protein DIS3 homolog ;
Ribosomal RNA-processing protein 44 ;
EC 3.1.26.- ;
Protein DIS3 homolog ;
Ribosomal RNA-processing protein 44 ;
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功能:
Function:Component of the exosome 3'->5' exoribonuclease complex. Required for the 3'-processing of the 7S pre-RNA to the mature nuclear complex. Also associated with the GTPase Ran. Has a 3'-5' exonuclease activity.,similarity:Belongs to the ribonuclease II (RNB) family.,similarity:Contains 1 PINc domain.,subunit:Component of the exosome multienzyme ribonuclease complex composed of at least 11 proteins: RRP4, RRP40, RRP41/SKI6, RRP42, RRP43, RRP44/DIS3, PM/Scl-75, RRP46, CSL4 and PM/Scl-100 (only in the nuclear complex). Also associated with the GTPase Ran.,tissue specificity:Widely expressed.,
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细胞定位:
Cytoplasm . Nucleus, nucleolus . Nucleus, nucleoplasm . Nucleus . Predominantly located in the nucleus (PubMed:20531386). According to PubMed:12429849, found in the nucleolus (PubMed:12429849). According to PubMed:20531386, excluded from nucleolus supporting the existence of a nucleolar RNA exosome complex devoid of DIS3 (PubMed:20531386). .
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组织表达:
Widely expressed.
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研究领域:
>>RNA degradation
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文献引用（{{totalcount}}）
货号: YN3292
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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