Synthesized peptide derived from human VATO AA range: 149-199

This antibody detects endogenous levels of VATO at Human/Mouse

ATP6V0B ATP6F

VATO

This gene encodes a portion of the V0 domain of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. Activity of this enzyme is necessary for such varied processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014],

Function:Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.,similarity:Belongs to the V-ATPase proteolipid subunit family.,tissue specificity:Ubiquitous.,

Cytoplasmic vesicle, clathrin-coated vesicle membrane ; Multi-pass membrane protein .

Ubiquitous.

>>Oxidative phosphorylation ;
>>Metabolic pathways ;
>>Lysosome ;
>>Phagosome ;
>>Synaptic vesicle cycle ;
>>Vibrio cholerae infection ;
>>Epithelial cell signaling in Helicobacter pylori infection ;
>>Tuberculosis ;
>>Human papillomavirus infection ;
>>Rheumatoid arthritis