FPR2 Rabbit pAb
-YN2518
主要信息
Target
FPR2
Host Species
Rabbit
Reactivity
Human, Rat, Mouse, Swine
Applications
WB, ELISA
MW
38kD (Observed)
Conjugate/Modification
Unmodified
货号: YN2518
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
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详细信息
推荐稀释比
WB 1:500-2000; ELISA 1:5000-20000
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
特异性
FPR2 Polyclonal Antibody detects endogenous levels of protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
38kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
Synthesized peptide derived from human protein . at AA range: 130-210
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特异性:
FPR2 Polyclonal Antibody detects endogenous levels of protein.
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基因名称:
FPR2 FPRH1 FPRL1 LXA4R
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蛋白名称:
N-formyl peptide receptor 2 (FMLP-related receptor I) (FMLP-R-I) (Formyl peptide receptor-like 1) (HM63) (Lipoxin A4 receptor) (LXA4 receptor) (RFP)
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背景:
function:Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4).,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed abundantly in the lung and neutrophils. Also found in the spleen and testis.,
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功能:
Function:Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4).,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed abundantly in the lung and neutrophils. Also found in the spleen and testis.,
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细胞定位:
Cell membrane ; Multi-pass membrane protein. Associates with Amyloid-beta protein 42, product of APP, at the cell surface and the complex is then rapidly internalized (PubMed:11689470). Also internalized in the presence of humanin (PubMed:15465011). .
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组织表达:
Detected in lung, bone marrow, neutrophils, spleen and testis.
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研究领域:
>>Neuroactive ligand-receptor interaction ;
>>Neutrophil extracellular trap formation ;
>>Staphylococcus aureus infection
>>Neutrophil extracellular trap formation ;
>>Staphylococcus aureus infection
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文献引用（{{totalcount}}）
货号: YN2518
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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