Synthetic peptide from human protein at AA range: 100-160

The antibody detects endogenous CD80

CD80 CD28LG CD28LG1 LAB7

T-lymphocyte activation antigen CD80 (Activation B7-1 antigen) (BB1) (CTLA-4 counter-receptor B7.1) (B7) (CD antigen CD80)

T-lymphocyte activation antigen CD80 ;
Activation B7-1 antigen ;
BB1 ;
CTLA-4 counter-receptor B7.1 ;
B7 ;
CD antigen CD80 ;

The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy. [provided by RefSeq, Aug 2011],

Function:Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Interacts with adenovirus subgroup B fiber proteins and acts as a receptor for these viruses.,tissue specificity:Expressed on activated B-cells, macrophages and dendritic cells.,

Membrane; Single-pass type I membrane protein.

Expressed on activated B-cells, macrophages and dendritic cells.

>>Cell adhesion molecules ;
>>Toll-like receptor signaling pathway ;
>>Intestinal immune network for IgA production ;
>>Type I diabetes mellitus ;
>>Autoimmune thyroid disease ;
>>Systemic lupus erythematosus ;
>>Rheumatoid arthritis ;
>>Allograft rejection ;
>>Graft-versus-host disease ;
>>Viral myocarditis