Function:Substrate of protein kinase PTK6. May play a regulatory role in the acute-phase response in systemic inflammation and may modulate STAT3 activity.,PTM:Phosphorylated on tyrosine. Tyr-250 may be important for interaction with kinases. Tyr-22 and Tyr-322 appears to be phosphorylated by SRC.,sequence Caution:Alu insert from position 358 to 403.,similarity:Contains 1 PH domain.,similarity:Contains 1 SH2 domain.,subunit:Interacts with PTK6 and CSF1R.,tissue specificity:Widely expressed.,
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