CCND2

G1/S-specific cyclin-D2

function:Essential for the control of the cell cycle at the G1/S (start) transition.,similarity:Belongs to the cyclin family.,similarity:Belongs to the cyclin family. Cyclin D subfamily.,subunit:Interacts with the CDK4 and CDK6 protein kinases to form a serine/threonine kinase holoenzyme complex. The cyclin subunit imparts substrate specificity to the complex.,

regulation of cyclin-dependent protein kinase activity, G1/S transition of mitotic cell cycle, mitotic cell cycle, ovarian follicle development, liver development, regulation of protein amino acid phosphorylation, positive regulation of protein amino acid phosphorylation, reproductive developmental process, cell cycle, gamete generation, spermatogenesis, sex differentiation, positive regulation of cell proliferation, gonad development, female gonad development, response to endogenous stimulus, response to hormone stimulus, response to organic substance, positive regulation of phosphorus metabolic process, positive regulation of macromolecule metabolic process, response to organic cyclic substance, regulation of phosphate metabolic process, sexual reproduction, cell cycle process, cell cycle phase,ovulation cycle process, regulation of protein modification process, positive regulation of protein modification process,regulation of cellular protein metabolic process, positive regulation of cellular protein metabolic process, response to estradiol stimulus, multicellular organism reproduction, response to insulin stimulus, cellular response to insulin stimulus, cellular response to hormone stimulus, response to testosterone stimulus, positive regulation of kinase activity, regulation of cell proliferation, regulation of phosphorylation, positive regulation of phosphorylation, ovulation cycle, positive regulation of catalytic activity, response to peptide hormone stimulus, regulation of kinase activity,response to estrogen stimulus, positive regulation of molecular function, development of primary sexual characteristics, response to ethanol, regulation of neuron differentiation, positive regulation of cyclin-dependent protein kinase activity, positive regulation of cell cycle, regulation of protein kinase activity, positive regulation of protein kinase activity, positive regulation of phosphate metabolic process, development of primary female sexual characteristics, female sex differentiation, male gamete generation, rhythmic process, response to steroid hormone stimulus, reproductive structure development, reproductive process in a multicellular organism, regulation of epithelial cell proliferation, positive regulation of epithelial cell proliferation, regulation of neurogenesis, regulation of phosphorus metabolic process, positive regulation of protein metabolic process, cell division, interphase, interphase of mitotic cell cycle, regulation of transferase activity, positive regulation of transferase activity, response to cAMP,regulation of cell cycle, regulation of nervous system development, regulation of cell development,

Nucleus . Cytoplasm . Nucleus membrane . Cyclin D-CDK4 complexes accumulate at the nuclear membrane and are then translocated into the nucleus through interaction with KIP/CIP family members. .; [Isoform 2]: Cytoplasm .