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R

GMEB1 (PT1099R) PT® Rabbit mAb

-YM8921

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主要信息
Target

GMEB1

Host Species

Rabbit

Reactivity

Human, Mouse, Rat

Applications

WB, IHC, ICC/IF, FC, IP

MW

63kDa (Calculated)

63kDa (Observed)

Conjugate/Modification

Unmodified

货号: YM8921
规格
价格
货期
数量
200μL
¥3,780.00
现货

0

100μL
¥2,300.00
现货

0

40μL
¥960.00
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0

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详细信息
推荐稀释比
IHC 1:200-1:1000; WB 1:1000-1:5000; IF 1:200-1:1000; IP 1:50-1:200; FC 1:100-1:500;
Note:For IHC,wesuggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004)
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
特异性
Endogenous
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
理论分子量
63kDa
实测条带
63kDa
修饰
Unmodified
克隆性
Monoclonal
克隆号
PT1099R
同种型
IgG,Kappa
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抗原&靶点信息
特异性:
Endogenous
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基因名称:
GMEB1
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蛋白名称:
Glucocorticoid modulatory element-binding protein 1 (GMEB-1) (DNA-binding protein p96PIF) (Parvovirus initiation factor p96) (PIF p96)
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数据库链接:
Organism 基因 ID SwissProt
Human 10691; Q9Y692;
Mouse 56809; Q9JL60 ;
Rat 500558; Q9QUZ8;
背景:
This gene encodes a member of KDWK gene family which associates with GMEB2 protein. The GMEB1-GMEB2 complex is essential for parvovirus DNA replication. Studies in rat for a similar gene suggest that this gene's role is to modulate the transactivation of the glucocorticoid receptor when it is bound to glucocorticoid response elements. Three alternative spliced transcript variants encoding different isoforms exist. [provided by RefSeq, Feb 2016]
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功能:
FUNCTION: Trans-acting factor that binds to glucocorticoid modulatory elements (GME) present in the TAT (tyrosine aminotransferase) promoter and increases sensitivity to low concentrations of glucocorticoids. Binds also to the transferrin receptor promoter. Essential auxiliary factor for the replication of parvoviruses.
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细胞定位:
SUBCELLULAR LOCATION: Nucleus. Cytoplasm. Note=May be also cytoplasmic.
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货号: YM8921
规格
价格
货期
数量
200μL
¥3,780.00
现货

0

100μL
¥2,300.00
现货

0

40μL
¥960.00
现货

0

加入购物车

已收藏

收藏

定制服务咨询

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