VMAT1 Rabbit pAb
-YN0590
主要信息
Target
VMAT1
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, ELISA
MW
57kD (Observed)
Conjugate/Modification
Unmodified
货号: YN0590
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
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详细信息
推荐稀释比
WB 1:500-2000; ELISA 1:5000-20000
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
特异性
VMAT1 Polyclonal Antibody detects endogenous levels of protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
57kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
Synthesized peptide derived from part region of human protein
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特异性:
VMAT1 Polyclonal Antibody detects endogenous levels of protein.
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基因名称:
SLC18A1 VAT1 VMAT1
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蛋白名称:
Chromaffin granule amine transporter (Solute carrier family 18 member 1) (Vesicular amine transporter 1) (VAT1)
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背景:
The vesicular monoamine transporter acts to accumulate cytosolic monoamines into vesicles, using the proton gradient maintained across the vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (Peter et al., 1993 [PubMed 7905859]). See also SLC18A2 (MIM 193001).[supplied by OMIM, Mar 2008],
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功能:
Function:Involved in the vesicular transport of biogenic amines.,similarity:Belongs to the major facilitator superfamily. Vesicular transporter family.,
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细胞定位:
[Isoform 1]: Cytoplasmic vesicle membrane ; Multi-pass membrane protein . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Multi-pass membrane protein .; [Isoform 2]: Endoplasmic reticulum membrane ; Multi-pass membrane protein .
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组织表达:
Highly expressed in chromaffin cells of the adrenal medulla (at protein level). Detected in peripheral sympathetic ganglia (at protein level). Found in some paracrine cells in stomach and duodenum (at protein level).
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研究领域:
>>Synaptic vesicle cycle ;
>>Serotonergic synapse ;
>>Dopaminergic synapse ;
>>Parkinson disease ;
>>Cocaine addiction ;
>>Amphetamine addiction ;
>>Alcoholism
>>Serotonergic synapse ;
>>Dopaminergic synapse ;
>>Parkinson disease ;
>>Cocaine addiction ;
>>Amphetamine addiction ;
>>Alcoholism
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信号通路
文献引用（{{totalcount}}）
货号: YN0590
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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