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ZBP1 Rabbit pAb

-YN2476

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主要信息
Target

ZBP1

Host Species

Rabbit

Reactivity

Human, Rat, Mouse,

Applications

WB, ELISA

MW

47kD (Observed)

Conjugate/Modification

Unmodified

货号: YN2476
规格
价格
货期
数量
200μL
¥3,780.00
现货

0

100μL
¥2,300.00
现货

0

40μL
¥960.00
现货

0

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详细信息
推荐稀释比
WB 1:500-2000; ELISA 1:5000-20000
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
特异性
ZBP1 Polyclonal Antibody detects endogenous levels of protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
47kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
Synthesized peptide derived from human protein . at AA range: 21-70
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特异性:
ZBP1 Polyclonal Antibody detects endogenous levels of protein.
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基因名称:
ZBP1 C20orf183 DLM1
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蛋白名称:
Z-DNA-binding protein 1 (Tumor stroma and activated macrophage protein DLM-1)
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数据库链接:
Organism 基因 ID SwissProt
Human 81030; Q9H171;
Mouse Q9QY24;
Rat Q8VDA5;
背景:
This gene encodes a Z-DNA binding protein. The encoded protein plays a role in the innate immune response by binding to foreign DNA and inducing type-I interferon production. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011],
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功能:
Alternative products:Additional isoforms seem to exist,Function:May play a role in host defense against tumors and pathogens. Binds Z-DNA.,similarity:Contains 2 DRADA repeats.,tissue specificity:Highly expressed in lymphatic tissues including lymph node, leukocytes, tonsil, bone marrow and spleen. Expressed to a lesser extent in thymus, lung and liver.,
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细胞定位:
Cytoplasm . Nucleus . Mainly cytoplasmic (PubMed:16876127, PubMed:16990255). Accumulates in the nucleus in response to influenza A virus (IAV) infection: senses IAV defective viral genomes RNA in the nucleus (By similarity). .; [Isoform 7]: Cytoplasm . Nucleus . Compared to isoform 1, a higher proportion of this isoform is localized in the nucleus. .
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组织表达:
Highly expressed in lymphatic tissues including lymph node, leukocytes, tonsil, bone marrow and spleen (PubMed:11842111). Expressed to a lesser extent in thymus, lung and liver (PubMed:11842111).
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研究领域:
>>Necroptosis ;
>>Cytosolic DNA-sensing pathway
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货号: YN2476
规格
价格
货期
数量
200μL
¥3,780.00
现货

0

100μL
¥2,300.00
现货

0

40μL
¥960.00
现货

0

加入购物车

已收藏

收藏

定制服务咨询

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