Gremlin-2 Rabbit pAb
-YT5894
主要信息
Target
Gremlin-2
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, IHC, IF, ELISA
MW
19kD (Observed)
Conjugate/Modification
Unmodified
货号: YT5894
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
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详细信息
推荐稀释比
WB 1:500-2000; IHC 1:500-200; ELISA 1:10000-20000; IF 1:50-200
Note:For IHC,wesuggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004)
Note:For IHC,wesuggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004)
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
The antibody detects endogenous Gremlin-2
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
19kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from the Internal region of human GREM2. AA range:71-120
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特异性:
The antibody detects endogenous Gremlin-2
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基因名称:
GREM2 CKTSF1B2 DAND3 PRDC
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蛋白名称:
Gremlin-2 (Cysteine knot superfamily 1, BMP antagonist 2) (DAN domain family member 3) (Protein related to DAN and cerberus)
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别名:
Gremlin-2 ;
Cysteine knot superfamily 1, BMP antagonist 2 ;
DAN domain family member 3 ;
Protein related to DAN and cerberus ;
Cysteine knot superfamily 1, BMP antagonist 2 ;
DAN domain family member 3 ;
Protein related to DAN and cerberus ;
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背景:
This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. [provided by RefSeq, Jul 2008],
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功能:
Function:Cytokine that inhibits the activity of BMP2 and BMP4 in a dose-dependent manner. Antagonized BMP4-induced suppression of progesterone production in granulosa cells.,similarity:Belongs to the DAN family.,similarity:Contains 1 CTCK (C-terminal cystine knot-like) domain.,subunit:Interacts with BMP2 and BMP4.,
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细胞定位:
Secreted .
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组织表达:
Brain,Colon,
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研究领域:
>>TGF-beta signaling pathway
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货号: YT5894
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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