Recombinant Human ACE2 protein
-YD2195
主要信息
Reactivity
Human
Applications
ELISA, ECL, Immunogold,
MW
86kD (Calculated)
100-110kD (Observed)
详细信息
推荐稀释比
Testing in progress
来源
Mammalian cells
纯度
>90% as determined by SDS-PAGE
储存
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
理论分子量
86kD
实测条带
100-110kD
抗原&靶点信息
基因名称:
ACE2
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蛋白名称:
ACE-related carboxypeptidase
Angiotensin-converting enzyme homolog
Metalloprotease MPROT15
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数据库链接:
| Organism | 基因 ID | SwissProt |
|---|---|---|
| Human | NP_001358344.1 or Q9BYF1; | Q9BYF1; |
| Mouse | Q8R0I0; |
背景:
Recombinant Human ACE2 is produced by Mammalian cells expression system and the target gene encoding Met1-Ser740 is expressed with C-HisTag
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功能:
Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don’t inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function.
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研究领域:
For research use only .Not for use in clinical diagnostic procedures.
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