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Calponin-1 (ABT133) Mouse mAb
-YM6827
主要信息
Target
Calponin-1
Host Species
Mouse
Reactivity
Human,
Applications
IHC, ELISA
MW
33kD (Calculated)
34kD (Observed)
Conjugate/Modification
Unmodified
详细信息
推荐稀释比
IHC 1:200-400; ELISA 1:500-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
特异性
The antibody can specifically recognize human and mouse calponin-1 protein.
纯化工艺
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
理论分子量
33kD
实测条带
34kD
修饰
Unmodified
克隆性
Monoclonal
克隆号
ABT133
同种型
IgG2a,Kappa
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抗原&靶点信息
免疫原:
Synthesized peptide derived from human Calponin-1 AA range: 100-200
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特异性:
The antibody can specifically recognize human and mouse calponin-1 protein.
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基因名称:
CNN1
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蛋白名称:
Calponin-1
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别名:
Calponin-1 ;
Basic calponin ;
Calponin H1, smooth muscle ;
Basic calponin ;
Calponin H1, smooth muscle ;
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功能:
Function:Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.,similarity:Belongs to the calponin family.,similarity:Contains 1 CH (calponin-homology) domain.,similarity:Contains 3 calponin-like repeats.,subunit:Part of cGMP kinase signaling complex at least composed of ACTA2/alpha-actin, CNN1/calponin H1, PLN/phospholamban, PRKG1 and ITPR1.,tissue specificity:Smooth muscle, and tissues containing significant amounts of smooth muscle.,
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细胞定位:
Cytoplasmic
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组织表达:
Smooth muscle, and tissues containing significant amounts of smooth muscle.
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