主要信息
Target
CD99
Host Species
Mouse
Reactivity
Human,
Applications
IHC
Conjugate/Modification
Unmodified
详细信息
推荐稀释比
Ready to use for IHC
组成
The prediluted ready-to-use antibody is diluted in phosphate buffer saline containing stabilizing protein and 0.05% Proclin 300
特异性
The antibody can specifically recognize human CD99 protein.
纯化工艺
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存
2°C to 8°C/1 year
修饰
Unmodified
克隆性
Monoclonal
克隆号
ABT156
同种型
IgG1,Kappa
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抗原&靶点信息
免疫原:
Synthesized peptide derived from human CD99 AA range: 1-100
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特异性:
The antibody can specifically recognize human CD99 protein.
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基因名称:
CD99 MIC2 MIC2X MIC2Y
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蛋白名称:
CD99
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别名:
CD99 antigen ;
12E7 ;
E2 antigen ;
Protein MIC2 ;
T-cell surface glycoprotein E2 ;
CD antigen CD99 ;
12E7 ;
E2 antigen ;
Protein MIC2 ;
T-cell surface glycoprotein E2 ;
CD antigen CD99 ;
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背景:
The protein encoded by this gene is a cell surface glycoprotein involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. In addition, the encoded protein may have the ability to rearrange the actin cytoskeleton and may also act as an oncosuppressor in osteosarcoma. This gene is found in the pseudoautosomal region of chromosomes X and Y and escapes X-chromosome inactivation. There is a related pseudogene located immediately adjacent to this locus. [provided by RefSeq, Mar 2016],
功能:
Function:Involved in T-cell adhesion processes. It is involved in spontaneous rosette formation with erythrocytes.,miscellaneous:The gene encoding for this protein is located in the pseudoautosomal region 1 (PAR1) of X and Y chromosomes.,PTM:Extensively O-glycosylated.,similarity:Belongs to the CD99 family.,
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细胞定位:
Membranous
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组织表达:
Membranous
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研究领域:
>>Cell adhesion molecules ;
>>Leukocyte transendothelial migration
>>Leukocyte transendothelial migration
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