联系我们

400-8787-807

快速订购

Glial Fibrillary Acidic Protein (GFAP) (ABT176) mouse mAb (Ready to Use)

-YM6877R

hot 2
货号: YM6877R
规格
价格
货期
数量
10mL
¥1,200.00
现货

0

6mL
¥900.00
现货

0

3mL
¥600.00
现货

0

加入购物车

已收藏

收藏

定制服务咨询
主要信息
Target

GFAP

Host Species

Mouse

Reactivity

Human, Rat, Monkey, Bovin,

Applications

IHC

Conjugate/Modification

Unmodified

详细信息
推荐稀释比
Ready to use for IHC
组成
The prediluted ready-to-use antibody is diluted in phosphate buffer saline containing stabilizing protein and 0.05% Proclin 300
特异性
The antibody can specifically recognize human GFAP protein.
纯化工艺
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存
2°C to 8°C/1 year
修饰
Unmodified
克隆性
Monoclonal
克隆号
ABT176
同种型
IgG2b,Kappa
相关产品
Secondary Antibodies
HRP* Goat Anti Mouse IgG(H+L)
RS0001

预览→

Secondary Antibodies
HRP* Goat Anti Rabbit IgG(H+L)
RS0002

预览→

Primary Antibodies
β-actin (PTR2364) mouse mAb
YM3028

预览→

Primary Antibodies
GAPDH (PTR2304) mouse mAb
YM3029

预览→

抗原&靶点信息
免疫原:
Synthesized peptide derived from human GFAP AA range: 300-432
展开内容
特异性:
The antibody can specifically recognize human GFAP protein.
展开内容
基因名称:
GFAP
展开内容
蛋白名称:
GFAP
展开内容
别名:
Glial fibrillary acidic protein ;
GFAP ;
展开内容
数据库链接:
Organism 基因 ID SwissProt
Human 2670; P14136;
背景:
This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008],
功能:
Alternative products:Isoforms differ in the C-terminal region which is encoded by alternative exons,Disease:Defects in GFAP are a cause of Alexander disease (ALEXD) [MIM:203450]. Alexander disease is a rare disorder of the central nervous system. It is a progressive leukoencephalopathy whose hallmark is the widespread accumulation of Rosenthal fibers which are cytoplasmic inclusions in astrocytes. The most common form affects infants and young children, and is characterized by progressive failure of central myelination, usually leading to death usually within the first decade. Infants with Alexander disease develop a leukoencephalopathy with macrocephaly, seizures, and psychomotor retardation. Patients with juvenile or adult forms typically experience ataxia, bulbar signs and spasticity, and a more slowly progressive course.,Function:GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.,online information:GFAP entry,similarity:Belongs to the intermediate filament family.,subcellular location:Associated with intermediate filaments.,subunit:Interacts with SYNM (By similarity). Isoform 3 interacts with PSEN1 (via N-terminus).,tissue specificity:Expressed in cells lacking fibronectin.,
展开内容
细胞定位:
Cytoplasmic
展开内容
组织表达:
Expressed in cells lacking fibronectin.
展开内容
研究领域:
>>JAK-STAT signaling pathway
展开内容
货号: YM6877R
规格
价格
货期
数量
10mL
¥1,200.00
现货

0

6mL
¥900.00
现货

0

3mL
¥600.00
现货

0

加入购物车

已收藏

收藏

定制服务咨询

Toggle night Mode

{{pinfoXq.title || ''}}

Catalog: {{pinfoXq.catalog || ''}}
Filter:

All

{{item.name}}

{{pinfo.title}}
-{{pinfo.catalog}}

筛选器:

{{item.descr}}

主要信息
Target
{{pinfo.target}}
Reactivity
{{pinfo.react}}
Applications
{{pinfo.applicat}}
Conjugate/Modification
{{pinfo.coupling}}/{{pinfo.modific}}
MW (kDa)
{{pinfo.mwcalc}}
Host Species
{{pinfo.hostspec}}
Isotype
{{pinfo.isotype}}
查看产品详情
产品 {{index}}/{{pcount}}
上一个产品
下一个产品

{{pvTitle}}

滚轮缩放图片
{{pvDescr}}