主要信息
Target
Glycophorin A
Host Species
Mouse
Reactivity
Human,
Applications
IHC
Conjugate/Modification
Unmodified
详细信息
推荐稀释比
Ready to use for IHC
组成
The prediluted ready-to-use antibody is diluted in phosphate buffer saline containing stabilizing protein and 0.05% Proclin 300
特异性
The antibody can specifically recognize human Glycophorin A protein.
纯化工艺
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存
2°C to 8°C/1 year
修饰
Unmodified
克隆性
Monoclonal
克隆号
ABT179
同种型
IgG1,Kappa
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抗原&靶点信息
免疫原:
Synthesized peptide derived from human Glycophorin A AA range: 1-100
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特异性:
The antibody can specifically recognize human Glycophorin A protein.
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基因名称:
GYPA GPA
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蛋白名称:
Glycophorin A
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别名:
Glycophorin-A ;
MN sialoglycoprotein ;
PAS-2 ;
Sialoglycoprotein alpha ;
CD antigen CD235a ;
MN sialoglycoprotein ;
PAS-2 ;
Sialoglycoprotein alpha ;
CD antigen CD235a ;
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背景:
Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. In addition to the M or N and S or s antigens that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta, as well as Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. [provided by RefSeq, Jul 2008],
功能:
Function:Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors and also binds influenza virus.,online information:Blood group antigen gene mutation database,polymorphism:Along with GYPB, GYPA is responsible for the MNS blood group system.,similarity:Belongs to the glycophorin A family.,
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细胞定位:
Membranous
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组织表达:
Cytoplasmic
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研究领域:
>>Hematopoietic cell lineage ;
>>Malaria
>>Malaria
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