主要信息
Target
S100P
Host Species
Mouse
Reactivity
Human,
Applications
IHC
Conjugate/Modification
Unmodified
详细信息
推荐稀释比
Ready to use for IHC
组成
The prediluted ready-to-use antibody is diluted in phosphate buffer saline containing stabilizing protein and 0.05% Proclin 300
特异性
The antibody can specifically recognize human S100P protein.
纯化工艺
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存
2°C to 8°C/1 year
修饰
Unmodified
克隆性
Monoclonal
克隆号
ABT229
同种型
IgG1,Kappa
相关产品
Primary Antibodies
S-100P Polyclonal Antibody
YT4203
预览→
Secondary Antibodies
HRP* Goat Anti Mouse IgG(H+L)
RS0001
预览→
Secondary Antibodies
HRP* Goat Anti Rabbit IgG(H+L)
RS0002
预览→
Primary Antibodies
β-actin (PTR2364) mouse mAb
YM3028
预览→
Primary Antibodies
GAPDH (PTR2304) mouse mAb
YM3029
预览→
抗原&靶点信息
免疫原:
Synthesized peptide derived from human S100P AA range: 1-95
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特异性:
The antibody can specifically recognize human S100P protein.
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基因名称:
S100P S100E
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蛋白名称:
S100P
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别名:
Protein S100-P ;
Protein S100-E ;
S100 calcium-binding protein P ;
Protein S100-E ;
S100 calcium-binding protein P ;
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背景:
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 4p16. This protein, in addition to binding Ca2+, also binds Zn2+ and Mg2+. This protein may play a role in the etiology of prostate cancer. [provided by RefSeq, Jul 2008],
功能:
miscellaneous:This protein binds two calcium ions.,similarity:Belongs to the S-100 family.,similarity:Contains 2 EF-hand domains.,subcellular location:Colocalizes with S100PBP in the nucleus.,subunit:Homodimer. Interacts with S100PBP and S100Z.,tissue specificity:Up-regulated in various pancreatic ductal adenocarcinomas and pancreatic intraepithelial neoplasias.,
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细胞定位:
Nuclear, Cytoplasmic
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组织表达:
Detected in all of the tissues except brain, testis and small intestine, expression level is higher in placenta, heart, lung, skeletal muscle, spleen and leukocyte. Up-regulated in various pancreatic ductal adenocarcinomas and pancreatic intraepithelial neoplasias.
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