主要信息
Target
Vimentin
Host Species
Mouse
Reactivity
Human, Mouse, Rat,
Applications
IHC
Conjugate/Modification
Unmodified
详细信息
推荐稀释比
Ready to use for IHC
组成
The prediluted ready-to-use antibody is diluted in phosphate buffer saline containing stabilizing protein and 0.05% Proclin 300
特异性
The antibody can specifically recognize human Vimentin protein.
纯化工艺
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存
2°C to 8°C/1 year
修饰
Unmodified
克隆性
Monoclonal
克隆号
ABT019
同种型
IgG2b,Kappa
相关产品
Primary Antibodies
Vimentin Polyclonal Antibody
YT4880
预览→
Primary Antibodies
Vimentin (Phospho Tyr38) Polyclonal Antibody
YP1209
预览→
Primary Antibodies
Vimentin (phospho Ser56) Polyclonal Antibody
YP0767
预览→
Primary Antibodies
Vimentin (phospho Ser83) Polyclonal Antibody
YP0766
预览→
Primary Antibodies
Vimentin (phospho Tyr61) Polyclonal Antibody
YP0275
预览→
ELISA Kits
Total VIM Cell-Based Colorimetric ELISA Kit
KA3428C
预览→
ELISA Kits
Phospho Vimentin (S56) Cell-Based Colorimetric ELISA Kit
KA1539C
预览→
ELISA Kits
Phospho Vimentin (S83) Cell-Based Colorimetric ELISA Kit
KA1538C
预览→
抗原&靶点信息
免疫原:
Synthesized peptide derived from human Vimentin AA range: 400-466
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特异性:
The antibody can specifically recognize human Vimentin protein.
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基因名称:
VIM
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蛋白名称:
ERK5
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别名:
Vimentin
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背景:
This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.[provided by RefSeq, Jun 2009],
功能:
Function:Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells.,online information:Vimentin entry,PTM:One of the most prominent phosphoproteins in various cells of mesenchymal origin. Phosphorylation is enhanced during cell division, at which time vimentin filaments are significantly reorganized.,sequence Caution:Intron retention.,similarity:Belongs to the intermediate filament family.,subunit:Homopolymer. Interacts with HCV core protein. Interacts with LGSN and SYNM.,tissue specificity:Highly expressed in fibroblasts, some expression in T- and B-lymphocytes, and little or no expression in Burkitt's lymphoma cell lines. Expressed in many hormone-independent mammary carcinoma cell lines.,
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细胞定位:
Cytoplasmic
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组织表达:
Highly expressed in fibroblasts, some expression in T- and B-lymphocytes, and little or no expression in Burkitt's lymphoma cell lines. Expressed in many hormone-independent mammary carcinoma cell lines.
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研究领域:
>>Epstein-Barr virus infection ;
>>MicroRNAs in cancer
>>MicroRNAs in cancer
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