主要信息
Target
Ki-67
Host Species
Rabbit
Reactivity
Human
Applications
IHC
Conjugate/Modification
Unmodified
详细信息
推荐稀释比
Ready to use for IHC
组成
The prediluted ready-to-use antibody is diluted in phosphate buffer saline containing stabilizing protein and 0.05% Proclin 300
特异性
The antibody can specifically recognize human Ki-67 protein.
纯化工艺
Recombinant Expression and Affinity purified
储存
2°C to 8°C/1 year
修饰
Unmodified
克隆性
Monoclonal
克隆号
ABT104R
同种型
IgG1,Kappa
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抗原&靶点信息
免疫原:
Synthesized peptide derived from human Ki-67
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特异性:
The antibody can specifically recognize human Ki-67 protein.
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基因名称:
MKI67
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蛋白名称:
Ki 67
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别名:
MKI67 ;
Antigen KI-67
Antigen KI-67
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背景:
This gene encodes a nuclear protein that is associated with and may be necessary for cellular proliferation. Alternatively spliced transcript variants have been described. A related pseudogene exists on chromosome X. [provided by RefSeq, Mar 2009],
功能:
developmental stage:Expression of this antigen occurs preferentially during late G1, S, G2 and M phases of the cell cycle, while in cells in G0 phase the antigen cannot be detected.,Function:Thought to be required for maintaining cell proliferation.,online information:Ki-67 entry,similarity:Contains 1 FHA domain.,subcellular location:Predominantly localized in the G1 phase in the perinucleolar region, in the later phases it is also detected throughout the nuclear interior, being predominantly localized in the nuclear matrix. In mitosis, it is present on all chromosomes.,subunit:Interacts with KIF15. Binds through the FHA domain to MKI67IP.,
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细胞定位:
Nuclear
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组织表达:
Nuclear
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