HMGB1 (PT0499R) PT® Rabbit mAb
-YM8327
主要信息
Target
HMGB1
Host Species
Rabbit
Reactivity
Human, Mouse, Rat,
Applications
WB, IHC, IF, IP, ELISA
MW
25kD (Calculated)
25kD (Observed)
Conjugate/Modification
Unmodified
货号: YM8327
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
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详细信息
推荐稀释比
IHC 1:2000-1:10000; WB 1:5000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
特异性
Endogenous
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
理论分子量
25kD
实测条带
25kD
修饰
Unmodified
克隆性
Monoclonal
克隆号
PT0499R
同种型
IgG,Kappa
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抗原&靶点信息
特异性:
Endogenous
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基因名称:
HMGB1 HMG1
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蛋白名称:
High mobility group protein B1 (High mobility group protein 1) (HMG-1)
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别名:
High mobility group protein B1 (High mobility group protein 1) (HMG-1)
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背景:
high mobility group box 1(HMGB1) Homo sapiens This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2015],
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功能:
Function:Binds preferentially single-stranded DNA and unwinds double stranded DNA.,similarity:Belongs to the HMGB family.,similarity:Contains 2 HMG box DNA-binding domains.,
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细胞定位:
Nucleus
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组织表达:
Ubiquitous. Expressed in platelets (PubMed:11154118).
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研究领域:
>>Base excision repair ;
>>Autophagy - animal ;
>>Necroptosis ;
>>Neutrophil extracellular trap formation
>>Autophagy - animal ;
>>Necroptosis ;
>>Neutrophil extracellular trap formation
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信号通路
文献引用（{{totalcount}}）
货号: YM8327
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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