TA2R Rabbit pAb
-YN2692
主要信息
Target
TA2R
Host Species
Rabbit
Reactivity
Human, Rat, Mouse
Applications
WB, ELISA
MW
37kD (Observed)
Conjugate/Modification
Unmodified
货号: YN2692
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
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详细信息
推荐稀释比
WB 1:500-2000; ELISA 1:5000-20000
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
特异性
TA2R Polyclonal Antibody detects endogenous levels of protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
37kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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RS0002
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YM3028
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抗原&靶点信息
免疫原:
Synthesized peptide derived from human protein . at AA range: 230-310
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特异性:
TA2R Polyclonal Antibody detects endogenous levels of protein.
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基因名称:
TBXA2R
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蛋白名称:
Thromboxane A2 receptor (TXA2-R) (Prostanoid TP receptor)
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背景:
thromboxane A2 receptor(TBXA2R) Homo sapiens This gene encodes a member of the G protein-coupled receptor family. The protein interacts with thromboxane A2 to induce platelet aggregation and regulate hemostasis. A mutation in this gene results in a bleeding disorder. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009],
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功能:
Disease:Defects in TBXA2R are the cause of a dominantly inherited bleeding disorder [MIM:188070].,Function:Receptor for thromboxane A2 (TXA2), a potent stimulator of platelet aggregation. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. In the kidney, the binding of TXA2 to glomerular TP receptors causes intense vasoconstriction. Activates phospholipase C. Isoform 1 activates adenylyl cyclase, isoform 2 inhibits adenylyl cyclase.,similarity:Belongs to the G-protein coupled receptor 1 family.,
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细胞定位:
Cell membrane; Multi-pass membrane protein.
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组织表达:
Blood,Endothelial cell,Lung,PCR rescued clones,Placenta,Platelet,
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研究领域:
>>Calcium signaling pathway ;
>>Neuroactive ligand-receptor interaction ;
>>Platelet activation
>>Neuroactive ligand-receptor interaction ;
>>Platelet activation
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信号通路
文献引用（{{totalcount}}）
货号: YN2692
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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