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GNAQ Rabbit pAb

-YN6244

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主要信息
Target

GNAQ

Host Species

Rabbit

Reactivity

Human, Mouse, Rat

Applications

WB

MW

39kD (Calculated)

Conjugate/Modification

Unmodified

货号: YN6244
规格
价格
货期
数量
200μL
¥3,780.00
现货

0

100μL
¥2,300.00
现货

0

40μL
¥960.00
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0

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详细信息
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
This antibody detects endogenous levels of GNAQ at Human, Mouse,Rat
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
理论分子量
39kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
Synthesized peptide derived from human GNAQ
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特异性:
This antibody detects endogenous levels of GNAQ at Human, Mouse,Rat
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基因名称:
GNAQ GAQ
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蛋白名称:
Guanine nucleotide-binding protein G(q) subunit alpha (Guanine nucleotide-binding protein alpha-q)
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数据库链接:
Organism 基因 ID SwissProt
Human 2776; P50148;
Mouse 14682; P21279;
Rat 81666; P82471;
功能:
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Regulates B-cell selection and survival and is required to prevent B-cell-dependent autoimmunity. Regulates chemotaxis of BM-derived neutrophils and dendritic cells (in vitro) (By similarity). Transduces FFAR4 signaling in response to long-chain fatty acids (LCFAs).
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细胞定位:
Cell membrane ; Lipid-anchor . Golgi apparatus . Nucleus . Nucleus membrane . Colocalizes with the adrenergic receptors, ADREN1A and ADREN1B, at the nuclear membrane of cardiac myocytes. .
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组织表达:
Predominantly expressed in ovary, prostate, testis and colon. Down-regulated in the peripheral blood lymphocytes (PBLs) of rheumatoid arthritis patients (at protein level).
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信号通路
Cellular Processes >> Cellular community - eukaryotes >> Gap junction Organismal Systems >> Immune system >> Platelet activation Organismal Systems >> Immune system >> Chemokine signaling pathway Organismal Systems >> Endocrine system >> Insulin secretion Organismal Systems >> Endocrine system >> Glucagon signaling pathway Organismal Systems >> Endocrine system >> GnRH signaling pathway Organismal Systems >> Endocrine system >> Estrogen signaling pathway Organismal Systems >> Endocrine system >> Oxytocin signaling pathway Organismal Systems >> Endocrine system >> Growth hormone synthesis, secretion and action Organismal Systems >> Endocrine system >> Aldosterone synthesis and secretion Organismal Systems >> Circulatory system >> Adrenergic signaling in cardiomyocytes Organismal Systems >> Circulatory system >> Vascular smooth muscle contraction Organismal Systems >> Nervous system >> Glutamatergic synapse Organismal Systems >> Nervous system >> Cholinergic synapse Organismal Systems >> Nervous system >> Dopaminergic synapse Organismal Systems >> Sensory system >> Inflammatory mediator regulation of TRP channels Human Diseases >> Cancer: overview >> Pathways in cancer Human Diseases >> Neurodegenerative disease >> Alzheimer disease Human Diseases >> Neurodegenerative disease >> Huntington disease Human Diseases >> Neurodegenerative disease >> Spinocerebellar ataxia Human Diseases >> Neurodegenerative disease >> Pathways of neurodegeneration - multiple diseases Environmental Information Processing >> Signal transduction >> Rap1 signaling pathway Environmental Information Processing >> Signal transduction >> Apelin signaling pathway Environmental Information Processing >> Signal transduction >> Calcium signaling pathway Environmental Information Processing >> Signal transduction >> Sphingolipid signaling pathway Environmental Information Processing >> Signal transduction >> cGMP-PKG signaling pathway
货号: YN6244
规格
价格
货期
数量
200μL
¥3,780.00
现货

0

100μL
¥2,300.00
现货

0

40μL
¥960.00
现货

0

加入购物车

已收藏

收藏

定制服务咨询

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