ADAMTS-16 Rabbit pAb
-YT0114
主要信息
Target
ADAMTS-16
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
IHC, IF, ELISA
MW
136kD (Calculated)
Conjugate/Modification
Unmodified
货号: YT0114
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
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详细信息
推荐稀释比
IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
ADAMTS-16 Polyclonal Antibody detects endogenous levels of ADAMTS-16 protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
理论分子量
136kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
Synthesized peptide derived from ADAMTS-16 . at AA range: 440-520
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特异性:
ADAMTS-16 Polyclonal Antibody detects endogenous levels of ADAMTS-16 protein.
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基因名称:
ADAMTS16
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蛋白名称:
A disintegrin and metalloproteinase with thrombospondin motifs 16
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别名:
ADAMTS16 ;
KIAA2029 ;
A disintegrin and metalloproteinase with thrombospondin motifs 16 ;
ADAM-TS 16 ;
ADAM-TS16 ;
ADAMTS-16
KIAA2029 ;
A disintegrin and metalloproteinase with thrombospondin motifs 16 ;
ADAM-TS 16 ;
ADAM-TS16 ;
ADAMTS-16
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背景:
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature protein, which may inhibit chondrosarcoma cell proliferation and migration. This gene may regulate blood pressure. [provided by RefSeq, May 2016],
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功能:
cofactor:Binds 1 zinc ion per subunit.,Domain:The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.,Domain:The spacer domain and the TSP type-1 domains are important for a tight interaction with the extracellular matrix.,PTM:The precursor is cleaved by a furin endopeptidase.,similarity:Contains 1 disintegrin domain.,similarity:Contains 1 peptidase M12B domain.,similarity:Contains 1 PLAC domain.,similarity:Contains 6 TSP type-1 domains.,tissue specificity:Expressed in fetal lung and kidney and in adult prostate and ovary.,
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细胞定位:
Secreted, extracellular space, extracellular matrix .
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组织表达:
Expressed in fetal lung and kidney and in adult prostate and ovary.
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文献引用（{{totalcount}}）
货号: YT0114
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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