IL-17Rα Rabbit pAb
-YT2318
主要信息
Target
IL-17Rα
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, ELISA
MW
90kD (Observed)
Conjugate/Modification
Unmodified
货号: YT2318
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
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详细信息
推荐稀释比
WB 1:500-1:2000; ELISA 1:40000; Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
IL-17Rα Polyclonal Antibody detects endogenous levels of IL-17Rα protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
90kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human IL17RA. AA range:141-190
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特异性:
IL-17Rα Polyclonal Antibody detects endogenous levels of IL-17Rα protein.
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基因名称:
IL17RA
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蛋白名称:
Interleukin-17 receptor A
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别名:
IL17RA ;
IL17R ;
Interleukin-17 receptor A ;
IL-17 receptor A ;
IL-17RA ;
CDw217 ;
CD antigen CD217
IL17R ;
Interleukin-17 receptor A ;
IL-17 receptor A ;
IL-17RA ;
CDw217 ;
CD antigen CD217
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背景:
Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2014],
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功能:
Function:Receptor for IL17A. Binds its ligand with low affinity, suggesting that additional components are involved in IL17A-induced signaling.,PTM:Glycosylated.,tissue specificity:Widely expressed.,
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细胞定位:
[Isoform 1]: Cell membrane ; Single-pass type I membrane protein .; [Isoform 2]: Secreted .
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组织表达:
Widely expressed.
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研究领域:
>>Cytokine-cytokine receptor interaction ;
>>IL-17 signaling pathway ;
>>Alcoholic liver disease
>>IL-17 signaling pathway ;
>>Alcoholic liver disease
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信号通路
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货号: YT2318
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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