Synthetic peptide from human protein at AA range: 61-110

The antibody detects endogenous CD300b

CD300LB CD300B CLM7 CMRF35A2 IREM3 LMIR5 TREM5 UNQ2530/PRO6029

CMRF35-like molecule 7 (CLM-7) (CD300 antigen-like family member B) (CMRF35-A2) (Immune receptor expressed on myeloid cells 3) (IREM-3) (Leukocyte mono-Ig-like receptor 5) (Triggering receptor expressed on myeloid cells 5) (TREM-5) (CD antigen CD300b)

CMRF35-like molecule 7 ;
CLM-7 ;
CD300 antigen-like family member B ;
CMRF35-A2 ;
Immune receptor expressed on myeloid cells 3 ;
IREM-3 ;
Leukocyte mono-Ig-like receptor 5 ;
Triggering receptor expressed on myeloid cells 5 ;
TREM-5 ;
CD antigen CD300b ;

CD300LB is a nonclassical activating receptor of the immunoglobulin (Ig) superfamily expressed on myeloid cells (Martinez-Barriocanal and Sayos, 2006 [PubMed 16920917]).[supplied by OMIM, Mar 2008],

Function:Acts as an activating immune receptor through its interaction with ITAM-bearing adapter TYROBP, and also independently by recruitement of GRB2.,PTM:Phosphorylation on Tyr-188 by FYN is required for interaction with GRB2.,similarity:Belongs to the CD300 family.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Interacts with TYROBP, which enhances cell surface expression and activation properties. Interacts with GRB2 in the presence of FYN.,tissue specificity:Expressed exclusively in myeloid lineages.,

Cell membrane ; Single-pass type I membrane protein .

Expressed exclusively in myeloid lineages.