Bradykinin B1 R Rabbit pAb
-YT0514
主要信息
Target
Bradykinin B1 R
Host Species
Rabbit
Reactivity
Human, Rat, Mouse,
Applications
WB, IF, ELISA
MW
40kD (Observed)
Conjugate/Modification
Unmodified
货号: YT0514
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
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详细信息
推荐稀释比
WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:5000; Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
Bradykinin B1 R Polyclonal Antibody detects endogenous levels of Bradykinin B1 R protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
40kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human BDKRB1. AA range:201-250
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特异性:
Bradykinin B1 R Polyclonal Antibody detects endogenous levels of Bradykinin B1 R protein.
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基因名称:
BDKRB1
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蛋白名称:
B1 bradykinin receptor
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别名:
BDKRB1 ;
BRADYB1 ;
B1 bradykinin receptor ;
B1R ;
BK-1 receptor
BRADYB1 ;
B1 bradykinin receptor ;
B1R ;
BK-1 receptor
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背景:
Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],
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功能:
Function:This is a receptor for bradykinin. Could be a factor in chronic pain and inflammation.,online information:Bradykinin receptor entry,similarity:Belongs to the G-protein coupled receptor 1 family.,
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细胞定位:
Cell membrane; Multi-pass membrane protein.
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组织表达:
Lung,Skin,
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研究领域:
>>Calcium signaling pathway ;
>>Neuroactive ligand-receptor interaction ;
>>Complement and coagulation cascades ;
>>Inflammatory mediator regulation of TRP channels ;
>>Regulation of actin cytoskeleton ;
>>Pathways in cancer
>>Neuroactive ligand-receptor interaction ;
>>Complement and coagulation cascades ;
>>Inflammatory mediator regulation of TRP channels ;
>>Regulation of actin cytoskeleton ;
>>Pathways in cancer
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信号通路
Cellular Processes >> Cell motility >> Regulation of actin cytoskeleton
Organismal Systems >> Immune system >> Complement and coagulation cascades
Organismal Systems >> Sensory system >> Inflammatory mediator regulation of TRP channels
Human Diseases >> Cancer: overview >> Pathways in cancer
Environmental Information Processing >> Signal transduction >> Calcium signaling pathway
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货号: YT0514
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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