GSDME N-terminal Rabbit pAb
-YT7990
主要信息
Target
GSDME
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
IF, WB, IHC
MW
36kD,55kD (Observed)
Conjugate/Modification
Unmodified
货号: YT7990
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
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详细信息
推荐稀释比
IF 1:50-200; WB 1:5000-20000; IHC 1:200-300
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
特异性
The antibody detects endogenous full lenth and n-ternal fragment of gsdme protein,
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
36kD,55kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
Synthesized peptide derived from human GSDME. AA range:1-100
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特异性:
The antibody detects endogenous full lenth and n-ternal fragment of gsdme protein,
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基因名称:
GSDME
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蛋白名称:
Gasdermin-E,DFNA5,Dfna5h,EG14210,2310037D07Rik .4932441K13Rik ,ICERE 1,ICERE-1,Deafness, autosomal dominant 5,Non-syndromic hearing impairment protein 5,GSDME-NT
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功能:
Cleavage at Asp-270 by CASP3 (mature and uncleaved precursor forms) or granzyme B (GZMB) relieves autoinhibition and is sufficient to initiate pyroptosis.
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细胞定位:
[Gasdermin-E, N-terminal]: Cell membrane ; Multi-pass membrane protein .; [Gasdermin-E]: Cytoplasm, cytosol .
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组织表达:
Expressed in cochlea (PubMed:9771715). Low level of expression in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas, with highest expression in placenta (PubMed:9771715).
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货号: YT7990
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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